A study in which all the participants are given a treatment and simply followed for a period of time to see if they improve, with no comparison against another group (control group) that is either taking another treatment or no treatment at all. The results of such studies can't be taken as evidence that a treatment works. Due to the
, one can be sure from the outset that most participants will improve; it is impossible to tell how much (if any) of this improvement is due to the effect of the treatment itself.
Uncontrolled studies can be quite useful, however, to find out whether a treatment causes any severe side effects.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.